PAX TECHNOLOGY - THE EFFECTIVE COMBINATION
OPTIMAL ELUTION OF PACLITAXEL
Pure paclitaxel applied using a microdrop spray crystallization process
Abluminal coating
Paclitaxel action:
- Anti-proliferative
- Anti-inflammatory
- Prevent Smooth Muscular Cells proliferation
- Promotes apoptosis at low doses
- Cytostatic within the therapeutic range
Safety and efficacy proven drug
* data on file
POLYMER-FREE
Shortcomings often associated with polymers during stent delivery
PAX technology = Polymer-free
Polymer-free coating:
- No inflammation
- Less thrombosis risk and better healing
* data on file
PRECLINICAL EVALUATION*
Histomorphometric analysis at 28 days
With PAX stents:
- Lower neo-intimal proliferation
- No increase of inflammation process
- No additional inflammation
- Complete coverage in all samples indicating complete re-endothelization
* data on file